Nope!

Just say no with this unique Nope Card Game by Ridley's Games. In this game you must try to keep your cards – this is the opposite to some other family games, so be careful! To begin the game, each player is dealt 7 cards and the remainder of the deck is placed in the centre to form the draw pile, then turn over the top card to start the discard pile.
The player to the left of the dealer begins by looking at the card on top of the discard pile. The top card tells you how many cards you must discard through its colour and the number: e.g. if it has the number 1 on it, you must discard 1. Note that the numbers on the cards serve no other function in the game. The colour/colours on the top card determine which colour cards you must discard. Some cards will only have 1 colour, others will have 2.
If you have the required cards place them down on the draw pile to end your turn. Remember – the card that you place on top will determine the next players go. If you cannot discard the required cards, pick one up from the draw pile (this is good) if you can then put down the cards, place them on the discard pile. If not, declare this to the group by saying “Nope!”. Your turn is now over.
There are also wild cards which contain all four colours and can be used to complete any set. In addition the pack contains 3 actions cards: Reset cards which end your go and force the next player to put down any card, Invisible cards which mean the next player must play as normal but refer to the card directly underneath the invisible card, and Nominate cards which mean you can nominate another player by name and declare how man cards they must discard: 1, 2 or 3.
This addictive colour-matching contest can be played with 2 or more players and is suitable for 6 years and above.

—description from the publisher